Protect Me From What I want has a sequel.
Protège Moi by Rae
http://spikeluver.com/SpuffyRealm/viewstory.php?sid=37201Summary: Sequel to 'Protect Me From What I Want' (which can also be found on this site)...Buffy and Spike's parents married when they were young and the two grew up as siblings, however through adolescence they drifted apart, and when circumstances reunited them they both started to battle strange feelings for one another, which eventually ended in them falling in love...picks up right where the first story left off, after months together they've finally reconciled their problems and the struggle they initially had with their relationship, and decide to go home to Sunnydale to tell their family...however when they return tragedy strikes causing them to postpone their announcement...will it bring them closer or threaten everything they've worked so hard to build? Complete
Spike is Buffy's step dad in this.
Window to the Soul by Starlight_Slayer
http://spikeluver.com/SpuffyRealm/viewstory.php?sid=37166&warning=NC-17Summary: Her love for him was forbidden...a childish dream in a world of harsh realities. But when tragedy strikes, can Spike and Buffy overcome the barriers to their love and pull closer together, or will the real world tear them apart? Complete
Six too Many by TammyAsh666
http://spikeluver.com/SpuffyRealm/viewstory.php?sid=20598Summary: Two completely different families are forced to live together when their parents get married. They learn to adjust to the new arrangement and find out that they might be more alike than they think. Spike finds himself drawn to his new step-sister, but will she feel the same way about him? What consequences would they have to deal with? Insider Tip runner up at the Cradle of Humanity Awards. Complete
Sweet Surrender by Sophie
http://spikeluver.com/SpuffyRealm/viewstory.php?sid=823Summary: COMPLETED ! Spike's mom, Joyce, married Buffy's dad, Giles, twelve years ago. They were raised like brother and sister. Spike has became a famous TV star and is engaged. Buffy stayed in Sunnydale where she works at the high school and dates Riley. Buffy's feeling for Spike were never the sisterly kind, but she bound them, thinking he could never love her back like she wanted him too. Unless... Complete
This is forever WIP.

It doesn't even end in a good place but it's already really long and has Spuffy.
The Attic by jennybean
http://spikeluver.com/SpuffyRealm/viewstory.php?sid=14468Summary: After the death of her husband, Joyce is forced to move with her four children back to Sunnydale to live with the parents that disowned her years ago. At Rayne Manor, siblings William and Elizabeth try to protect their family from their evil grandmother Drusilla, while uncovering secrets of the past and creating a few of their own. Loosely based on the book 'Flowers in the Attic.' WARNING: Will eventually deal with incest. WIP
Touch Myself by blatravis
http://spikeluver.com/SpuffyRealm/viewstory.php?sid=24247Summary: What's a guy to do, when he catches his step-sister doing something naughty? This is my first fic, so please be nice

This fic deals with incest, so if you dont like that kind, then please dont read. Complete
Summer Skin by Vanilla
http://dark-solace.org/elysian/viewstory.php?sid=2449&ageconsent=okSummary:
Step-siblings Buffy and Spike have worked very hard not to give in to the wild passion flaring between them over the years, but now that they're both single, the dangers of them actually giving in to what they want will rise...Written for the taboo_spuffy community mini challenge on LiveJournal. Complete
Dancing with fate. by Spikes_slayer08
http://dark-solace.org/elysian/viewstory.php?sid=3269&warning=NC-17Summary: AU all human fic. WARNING: this is a half sibling fic (same dad) if that's not for you then go no further otherwise enjoy. Buffy and Spike are half siblings who have the same father but Spike has spend the past two years fighting his attraction to Buffy and with only two weeks left before he leaves for college he thinks he is home free but when their parents decided to go away on a second honeymoon Spike finds himself alone for the full two weeks with the object of his every desire. Complete